Well first of all it is usually difficult to gain muscle while you are trying to lose weight. Make sure you are getting enough protien. I say about 1 gram of protien for every pound of body weight maybe even a little more. As far as being tired goes, maybe you should cut back on running a little if you are gonna run before lifting or else run after you lift. You could also try a pre-workout drink and take it after you are done with your running. A meal with some carbs about an hour before you workout will help too.
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